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Meiosis
   
Meiosis 15 by GreenFlames09 on Flickr

The first and longest phase of meiosis, Prophase I, occurs as the nuclear envelope disappears, centrosomes (#5) begin to migrate to opposite poles of cell, and chromatin condenses to form visibly thick chromosomes.
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Meiosis 4 by GreenFlames09 on Flickr

In phase II, Metaphase I, homologous chromosomes, attached to spindle fibers, are pulled to the center of the cell.  

  • Karyotypes are constructed as pictographs of this stage.
  • Chromosomes appear as tetrads, composed of 4 sister chromotids.  
  • Overlapping pieces can swap chromosomes (crossing over), even between nonsister chromosomes (chiasmata).  
  • Crossing over can occur multiple times in the same chromosomes.

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Meiosis 7 by GreenFlames09 on Flickr

In the 3rd phase, Anaphase I, the sister chromosomes are pulled toward the opposite poles.
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Meiosis 1 by GreenFlames09 on Flickr


Telophase I & cytokinesis = end of meiosis I

-->2 diploid cells = 2 copies of their DNA  (2n).

  • Meiosis II begins.  Each of these cells repeats Prophase to Telophase -->4 haploid cells =  only 1 copy of DNA (1 n).
  • The  production of egg cells is called oogenesis and results in 1 ovum & 3 polar bodies. 
  • The production of sperm cells is called spermatogenesis and results in 4 spermatids/ sperm.
  • In humans, each egg then has 1 X sex chromosome + 22 autosomes.  
  • Each sperm carries either an X or a Y sex chromosome + 22 corresponding autosomes. 
  • When fertilization occurs, the sperm's DNA is transferred to the ovum, resulting in the formation of a zygote with a full set of 46 chromosomes (23 pairs).

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Meiosis 14 by GreenFlames09 on Flickr


Note in Meiosis II only sister chromatids are joined together.  Crossing over has likely occured in Metaphase I.
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